Original paper
1. Palmitate-induced lipotoxicity is crucial for the pathogenesis of nonalcoholic
fatty liver disease
in cooperation with gut-derived endotoxin
Ogawa Y, Imajo K, Honda Y, Kessoku T, Tomeno W, Kato S, Fujita K, Yoneda
M, Saito S, Saigusa Y, Hyogo H,
Sumida Y, Itoh Y, Eguchi K, Yamanaka T, Wada K, Nakajima A.
Scientific Reports. 8:11365, 2018
2. Efficacy, safety, and tolerability of lubiprostone for the treatment
of non-alcoholic fatty liver disease in adult patients
with constipation: The LUBIPRONE, double-blind, randomised, placebo-controlled
study design.
Kessoku T, Imajo K, Kobayashi T, Honda Y, Kato T, Ogawa Y, Tomeno W,
Kato S, Higurashi T, Yoneda M,
Kirikoshi H, Kubota K, Taguri M, Yamanaka T, Usuda H, Wada K, Saito S, Nakajima A.
Contemporary Clinical Trials. 69:40-47, 2018.
3. Activated protein C suppresses osteoclast differentiation via endothelial
protein C receptor, protease-activated receptor-1,
sphingosine 1-phosphate receptor, and apolipoprotein E receptor 2.
Yoshida K, Akita N, Okamoto T, Asanuma K, Uchida A, Sudo A, Shimaoka M, Suzuki K, Hayashi T.
Thrombosis Research. 163:30-40, 2018
4. Reduced substrate stiffness promotes M2-like macrophage activation and
enhances peroxisome proliferator-activated
receptor γ expression.
Okamoto T, Takagi Y, Kawamoto E, Park EJ, Usuda H, Wada K, Shimaoka M.
Experimental Cell Research. 367:264-273, 2018.
5. A Potential New Risk Factor for Stroke: Streptococcus Mutans With Collagen-Binding
Protein.
Inenaga C, Hokamura K, Nakano K, Nomura R, Naka S, Ohashi T, Ooshima
T, Kuriyama N, Hamasaki T,
Wada K, Umemura K, Tanaka T.
World Neurosurgery. 113:e77-e81, 2018
6. Oral microbiome alterations of healthy volunteers with proton pump inhibitor.
Mishiro T, Oka K, Kuroki Yi, Takahashi M, Tatsumi K, Saitoh T, Tobita
H, Ishimura N,
Sato S, Ishihara S, Sekine J, Wada K, Kinoshita Y.
Journal of Gastroenterology and Hepatology. 33:1059-1066, 2018
7. Wisteria floribunda agglutinin-positive Mac-2-binding protein and type
4 collagen 7S: useful markers for the diagnosis of
significant fibrosis in patients with non-alcoholic fatty liver disease.
Ogawa Y, Honda Y, Kessoku T, Tomeno W, Imajo K, Yoneda M, Kawanaka M, Kirikoshi H, Ono M,
Taguri M, Saito S,
Yamanaka T, Wada K, Nakajima A
Journal of gastroenterology and hepatology. 33:1795-1803, 2018
International conference
1. Endothelial cell reduces gap junction intercellular communication and
increases cellular stiffness upon inflammation
Okamoto T, Kawamoto E., Shimaoka M, Usuda H, Wada K.
World Congress of Basic and Clinical Pharmacology, 2018, Kyoto
2 .Histological detection of mmcp-4 expressing cells by in situ RT-PCR
method.
Tanaka T, Asano S, Niibayashi T, Usuda H, Okamoto T, Wada, K.
World Congress of Basic and Clinical Pharmacology, 2018, Kyoto
3. Novel method for evaluating leaky gut syndrome induced by NSAIDs/PPI
and ischemia
with health food-derived reagent
Usuda H, Niibayashi T, Tanaka T, Okamoto T, Wada K.
World Congress of Basic and Clinical Pharmacology, 2018, Kyoto