Research Theme

In our research lab, our work is concerned with revealing how cancer arises, how it metastasizes, and how it can be prevented. We are conducting research using cultivated cells and fission yeast to investigate the control mechanisms of cell cycles, with particular attention to cell division with cyclin dependent kinases, and heterochromatin in chromosome dynamics. Employing biochemical and molecular biological approaches, and with emphasis on ‘visualization’ using fluorescent protein and monoclonal antibodies, our research is of the highest quality. It is our hope that the results of our research will prove useful in the treatment of patients.

Content

1. In cell cycles, analysis of cyclin dependent kinases in G2/M period.
2. Elucidation of control mechanism in chromosome dynamics.
3. Elucidation of molecular mechanism for heterochromatin.
4. Visualization of spatiotemporal behavior in protein.
5. Engineering of monoclonal antibodies for site-specific post-translation modification in phosphorylation and methylation.